2021.12.09 11:00 EchoingTime Easiest way to hit some targets (aftermath)
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2021.12.09 11:00 jimmywaleseswhale Is this the real deal? The ambassador tag stitching seems off
2021.12.09 11:00 BulletBreak steal his look
|submitted by BulletBreak to HalfLife [link] [comments]|
2021.12.09 11:00 BagInteresting1850 Any advice a young 19M should know before trying dating again?
I feel like im ready to try again, ive had some weird dynamics in the past.
Ive felt kinda used, not included etc. In the past.
I wanna know from people whove had more experience than me, what should i look for in a girl?
submitted by BagInteresting1850 to dating_advice [link] [comments]
2021.12.09 11:00 Simpapulya the lizards have a guard
|submitted by Simpapulya to Catswithjobs [link] [comments]|
2021.12.09 11:00 Ok-Camera-6967 SGP’s for TNF?
2021.12.09 11:00 rangeiscold ITAP of a National Cemetery
|submitted by rangeiscold to itookapicture [link] [comments]|
2021.12.09 11:00 SouthBound2025 What next? Not yet happy
Recent acquisition of Hisense U8G prompted a round of audio upgrades. Problem is, I'm not yet super happy with the results. Looking for suggestions.
By far the most audio magic happening is with my Bose QC 35 II headphones courtesy of steaming apps via BT AAC with Android Adapt Sound and small tweak to EQ.
Here is where I am...all still in 45 day demo period.
Denon S-760 AVR Q Acoustics Q3020i SVS PB 1000
All calibrated with various test tones and SPL meter, old school.
What are my complaints?
System feels congested during complex dynamics.
System not even close in resolution and balance to the headphones.
Total budget = $1500 (includes returns)
submitted by SouthBound2025 to BudgetAudiophile [link] [comments]
2021.12.09 11:00 farklinkbot Photoshop this technology
2021.12.09 11:00 81g_Chungu5 Ive lost all hope in humanity
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2021.12.09 11:00 ArkForever2020 [PC Server] Ark Forever - The #1 PVP/ORP No-Wipe Cluster In Existence - 7 Day New Player Protection
2021.12.09 11:00 farklinkbot The father and son who allegedly sparked the Caldor Fire together get arrested for reckless arson together. Still no arrests in the Bradlees or Sears fires
|submitted by farklinkbot to fark [link] [comments]|
2021.12.09 11:00 Rosengreen92 Soonaverse WAGMI
I call upon every community member with just the slightest interest in the new Soonaverse space to try it out! Just get started aldready! Set up your Metamask account (https://metamask.io/) and connect it to the EVM: https://wiki.iota.org/smart-contracts/guide/chains_and_nodes/testnet
I am a super-noob in this space, but I figured it out rather easily. Join the WAGMI community movement once you have entered Sooanverse if you found this helpful at all, and get a cool firstmover badge! ITS COMPLETELY FREE!
submitted by Rosengreen92 to Iota [link] [comments]
2021.12.09 11:00 speculo3 [USA-FL] [H] EVGA GTX 1080 Ti Hybrid [W] PayPal, Cash
Hello, thanks for taking the time to read.
I recently got my hands on a 3000 series card, which is the only reason I’m selling this beast. It has never been mined on, and has been well taken care of. On eBay, these completed/sold cards are around $750-$850. Looking to get around $800, but am open to negotiation. Please let me know if I can answer any additional questions. Thanks!
submitted by speculo3 to hardwareswap [link] [comments]
2021.12.09 11:00 Dhairya09ll 🗣️ GetSafle Introduced Paging Announcement for all SafleNauts Our IDO Whitelist on polkastarter is now live! 👨🏽🚀💫 📆: December 7 - December 13 More Details: https://t.co/vOFezjxql2
|submitted by Dhairya09ll to cryptohangout [link] [comments]|
2021.12.09 11:00 AdvancedFactor1896 I want to start running outdoors as an exercise but just feel awkward doing it. Do you have any tips on how to feel less awkward ?
2021.12.09 11:00 VimVinyl Best Chow Spots
2021.12.09 11:00 Firm_Trouble_1904 How is the big time. I am the same guy with a different account. I am giving away 500 commons. THE CHRISTMAS SPIRIT IS HERE!!! Comment down below if you want a common.
2021.12.09 11:00 Seed2_0 Can't set the maximum RAM on my raspberry pi
Hi there! So I bought a raspberry pi 4 model B with 8 gigabyte of RAM. I sucsessfully made my Minecraft server but when I try to set the maximum memory usage from 2gigabytes to 3 or four gigabytes I can't. It always returns with an error message here is my server start code:
java -Xms2048M -Xmx3G -jar /home/pi/minecraft/spigot-1.18 nogui
Can somebody help me set the maximum memory for the server?
Sorry for my bad english, I'm not an expert in this language.
submitted by Seed2_0 to admincraft [link] [comments]
2021.12.09 11:00 umaradil Do people think that they will be left (at ease) only on their saying, “We believe” and will not be put to any test? (Al-Ankaboot 1)
|submitted by umaradil to TheUnitedUmmah [link] [comments]|
2021.12.09 11:00 Diligent_Cause CytoDyn Submits Protocol with the FDA for Phase 3 Registrational Trial of Leronlimab for Critically Ill COVID-19 Population
During recent discussions with the FDA, the agency suggested that developing leronlimab for critically ill COVID-19 patients in current situation in U.S. appears feasible
VANCOUVER, Washington--(BUSINESS WIRE)-- CytoDyn Inc. (OTCQB: CYDY) (“CytoDyn” or the “Company”), a late-stage biotechnology company developing leronlimab, a CCR5 antagonist with the potential for multiple therapeutic indications, today announced that it has submitted a Phase 3, randomized, double blind, placebo controlled trial with the U.S. Food and Drug Administration (“FDA”) to evaluate the efficacy and safety of leronlimab in combination with standard of care for critically ill patients with COVID-19 pneumonia with need for invasive mechanical ventilation ("IMV”) or Extracorporeal Membrane Oxygenation (“ECMO”).
In CytoDyn’s recent discussions with the FDA regarding potential marketing approval of leronlimab for critically ill COVID-19 population, the agency stated: “While there are currently fewer U.S. patients hospitalized for COVID-19 daily in the U.S. compared to when you submitted your initial request for an expanded access protocol in August 2021, the CDC reports that 38,332 patients were hospitalized daily in the U.S. during the week of November 7th-13th, 2021. In this context, conducting a clinical trial in the U.S. that could support marketing approval of leronlimab for the treatment of critically ill patients with COVID-19 appears feasible.”
If approved by the FDA, patients in this trial will be randomized in a 1:1 ratio to receive up to four doses of 700 mg leronlimab with standard of care or placebo with standard of care administered by 30-minute IV infusion weekly over a four-week treatment period.
The subgroup analyses of 62 critically ill patients in the past Phase 3 CD12 trial for severe-to-critically ill population in the U.S. showed an 82% survival benefit at Day 14 after two doses of leronlimab on Day 0 and Day 7 (Odd Ratio 0.09 (CI 0.01, 0.72), p-value 0.0233) vs. standard of care plus placebo. The survival benefit fell from 82% to 30% after four weeks.
Nitya Ray, Ph.D., CytoDyn’s Chief Operating and Technology Officer, commented, “We expect further improvement in survival benefit in the new study with four weekly doses of leronlimab delivered by IV infusion. With IV dosing, the bioavailability and peak serum concentration of leronlimab will be much better compared to subcutaneous (“SC”) dosing. Furthermore, while the maximum serum concentration is achieved in less than two hours for IV infusion, it takes two to three days to reach the peak concentration in a SC setting. This is crucial in our view, especially for the critically ill patients who are on IMV or ECMO when every moment counts.”
Nader Pourhassan, Ph.D., CytoDyn’s President and Chief Executive Officer, commented, “Entering Phase 3 of the developmental trial is an exciting opportunity as we further explore leronlimab’s viability as a treatment option for critically ill COVID-19 patients. We are optimistic that the new trial with 4 dosages of leronlimab instead of the previous trial with 2 dosages will have much better outcome. We are very proud of our COVID-19 development team conducting two Phase 3 trials in Brazil while pursuing two more in the U.S. (critically ill and long-haulers). We have worked very hard to place our Company in a solid position in areas of HIV, Cancer, NASH, and COVID-19 and 2022 we believe will be a great year for us.”
submitted by Diligent_Cause to LeronLimab_Times [link] [comments]
2021.12.09 11:00 Political_news69 Industry, investors bank on no coal power by 2043, market operator says
2021.12.09 11:00 r_nimator2006o Being able to use stuns on a ragdolled person is the stupidest shit ong
2021.12.09 11:00 FrankB11 Why doesn’t PK Subban get disciplined for repeated slew footing?
Seems strange to me that a guy can repeatedly slew foot, sometimes resulting in injury to his victims, yet the league does nothing about it.
The next time PK slew foots, and there almost certainly will be a next time, how does the league justify their inaction?
What happens if the next slew-foot results in a career-ending injury?
submitted by FrankB11 to nhl [link] [comments]
2021.12.09 11:00 AusQ2021 What do you think ?